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1 <br /> 5. <br /> September 23,2002 <br /> Dr.Summers <br /> Page 2 <br /> chipped on walls or ceilings;uncertainty about whether concrete floors were sealed;and <br /> presence of lay-in,acoustic tile ceilings. " <br /> Sanitation practices should be reviewed,in particular the effective"shelf life"of bleach <br /> solutions.We're not certain what those guidelines should be,but a week between changes of <br /> bleach baths may be excessive to ensure effectiveness;presence of organic matter may <br /> compromise effectiveness even sooner.(Are fresh solutions made daily for cage cleaning?)Foot <br /> baths have inherent shortcomings,i.e.,rapid build up of organic matter and difficulty in ensuring <br /> adequate contact with shoes,including adequate contact time.In our facilities,it is more typical <br /> to use disposable shoe covers when contamination by this route is of concern. <br /> We discussed possible limitations in use of a hand disinfectant;we're not aware of actual data <br /> that would help judge whether this is actually effective in killing parvoviruses.One consideration <br /> would be for staff to use disposable gloves when working in quarantine/isolation,or perhaps <br /> even routinely during an outbreak.We didn't discuss other fomites,but this is an important <br /> consideration in preventing transmission of infectious agents among animals.What protective <br /> clothing is used by staff when handling animals?In our facilities,it is typical in <br /> quarantine/isolation conditions for personnel to change outerwear(anywhere from lab coats to <br /> full-dress coveralls with cap,boots,and gloves)for each such room.In some cases;the <br /> protective clothing is left in the room and re-used but,with higher level concern,new disposable <br /> apparel is used by each person each time they enter.We didn't ask about the shelter cat,but she <br /> also is a potential fomite.Wild mice also have the potential to act as fomites,although we're not <br /> aware of specific data to indicate this for feline and canine parvovimses. <br /> It's useful in an outbreak situation,and perhaps routinely,to think in terms of susceptible <br /> individuals;infection can only be spread/maintained in a facility if there are susceptible animals <br /> exposed to those that are shedding the virus.We don't know with respect to the outbreak this <br /> past Spring to what extent the infection continued because of incoming infected,.animals <br /> compared with maintenance in the facility,but this seems an important consideration to attempt. <br /> Sanitation practices and traffic patterns can minimize transmission within the facility,and <br /> effective quarantine can minimize exposure of healthy animals to new arrivals.Vaccination on <br /> arrival seems prudent,but if an incoming animal has no immunity when it arrives,this <br /> vaccination would not prevent disease if it exposure occurs shortly thereafter.This means that <br /> effective quarantine is key and,given the incubation period of the virus,the length of quarantine <br /> (or at least time before adoption)will be important in preventing adoption of animals that have <br /> been exposed but not yet showing signs.Can/should pre-weaning kittens be vaccinated? <br /> It seems inappropriate for us to judge the proper level of euthanasia in the face of an outbreak; <br /> clearly there are competing,if not conflicting,shelter objectives.To the extent that the adoption <br /> of healthy animals is a key objective,it may be necessary in an outbreak to decrease the number <br /> of adoptions,increase the holding period and/or limit public access to certain areas of the shelter. <br /> Effective biosecurity should control the public as well as shelter staff. <br /> One consideration we didn't discuss was the role of the spay/neuter program in a disease <br />