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• Science has not kept pace with e- cigarette development and use <br />growth to inform policy at the national, state, county, or municipal level <br />• Areas of most knowledge <br />- Usage rates in adult and youth populations <br />- Toxicity of e- cigarette emissions (generically) <br />• Areas of least knowledge <br />- Potential for secondary or tertiary exposure <br />- Acute and chronic health impacts on user or others <br />